2-(BROMOACETYL)PYRIDINE HYDROBROMIDE

2-(BROMOACETYL)PYRIDINE HYDROBROMIDE - Names and Identifiers

Name	2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide
Synonyms	TIMTEC-BB SBB005581 2-bromo-1-(pyridin-2-yl)ethanone 2-(bromoacetyl)pyridinium bromide 2-(Bromoacetyl)pyridine hydrobromide 2-(BROMOACETYL)PYRIDINE HYDROBROMIDE 2-(2-BROMOACETYL)PYRIDINE HYDROBROMIDE 2-BROMO-1-PYRIDIN-2-YL-ETHANONE HYDROBROMIDE 2-Bromo-1-(2-pyridinyl)ethanone hydrobromide 2-bromo-1-(pyridin-2-yl)ethanone hydrobromide 2-BROMO-1-(2-PYRIDINYL)-1-ETHANONE HYDROBROMIDE 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide
CAS	17570-98-8
InChI	InChI=1/C7H6BrNO.BrH/c8-5-7(10)6-3-1-2-4-9-6;/h1-4H,5H2;1H

2-(BROMOACETYL)PYRIDINE HYDROBROMIDE - Physico-chemical Properties

Molecular Formula	C7H7Br2NO
Molar Mass	280.94
Melting Point	205 °C
Boling Point	249.1°C at 760 mmHg
Flash Point	104.5°C
Vapor Presure	0.0233mmHg at 25°C
Appearance	Solid
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

2-(BROMOACETYL)PYRIDINE HYDROBROMIDE - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant

2-(BROMOACETYL)PYRIDINE HYDROBROMIDE - Introduction

2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is an organic compound with the chemical formula C8H8BrNO2.

Nature:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is a white crystalline solid. It is soluble in water and organic solvents at room temperature. It is stable, but may decompose when exposed to high temperatures, strong oxidants or strong acids.

Use:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is a commonly used organic synthesis intermediate. It can be used in the synthesis of pyrrole derivatives, imidazoles and other organic chemical reactions.

Method:
The preparation of 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide is usually obtained by the reaction of pyridine and bromoacetic acid. The specific preparation steps are as follows:
1. Slowly add pyridine to glacial acetic acid under cooling.
2. Bromoacetic acid was slowly added to the above reaction system, and the reaction mixture was heated.
3. After the completion of the reaction, the solution was concentrated sulfuric acid extraction.
4. The concentrated sulfuric acid transparent liquid is washed and concentrated to finally obtain 2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide.

Safety Information:
2-bromo-1-(2-pyridinyl)-1-ethanone hydrobromide has no obvious acute toxicity under normal use conditions. However, it is an organic acid and may have an irritating effect on the skin, eyes and respiratory system. Care should be taken to avoid contact with skin and eyes, and appropriate protective measures should be taken during operation, such as wearing gloves, goggles and protective clothing. Pay attention to ventilation during use and avoid reaction with strong oxidants or strong acids. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15